Adrafinil is a mild stimulant of the central nervous system that is used to relieve excessive sleepiness and inattention. It is also used off-label by individuals including night shift workers who need to stay alert and awake for long periods of time. It was originally developed to increase wakefulness in narcoleptics. Adrafinil gives you more energy with a “caffeine jitters” feeling.
Adrafinil is a “prodrug” as it is first metabolized by the body into an active pharmacological agent, modafinil. However, the metabolite takes around 45-60 minutes to accumulate to active levels in the bloodstream when taken orally on an empty stomach.
The popular theory suggests that Adrafinil increases the brain neurotransmitter, hypocretin, which keeps the individuals alert and awake. An increased level of hypocretin in the hypothalamus is thought to increase the levels of dopamine, norepinephrine and histamine, which accounts for the main nootropic action of Adrafinil and Modafinil.
Adrafinil enhances cognition, mental alertness and memory, while it is also known to be useful in treating those with ADHD symptoms. Adrafinil is currently unregulated and has not been approved for any clinical uses or human consumption by the U.S. Food and Drug Administration.
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